Kwinkalo yokupakishwa kwezonyango, iibhotile ze-polypropylene (PP) ziye zaba yifom yokupakisha ye-intravenous infusion (IV) isisombululo ngenxa yokuzinza kweekhemikhali ezigqwesileyo, ukumelana nobushushu obuphezulu, kunye nokhuseleko lwezinto eziphilayo. Ngokukhula kwemfuno yonyango yehlabathi kunye nokuphuculwa kwemigangatho yoshishino lwamayeza, i-PP ezenzekelayo ngokupheleleyo ibhotile ye-IV imigca yokuvelisa isisombululo iya iba ngumgangatho kwishishini. Eli nqaku liza kwazisa ngokucwangcisiweyo ukubunjwa kwezixhobo ezingundoqo, izibonelelo zobugcisa, kunye nethemba lemarike ye-PP bottle IV yomgca wokuvelisa isisombululo.

Izixhobo ezingundoqo zomgca wokuvelisa: ukuhlanganiswa kweemodyuli kunye nentsebenziswano echanekileyo ephezulu

EyangokuPP ibhotile IV umgca wokuvelisa isisombululoinezixhobo ezithathu ezingundoqo: umatshini wokutofa we-preform/ihanger, umatshini wokubumba wokuvuthela, kunye nokucoca, ukuzalisa, kunye nomatshini wokutywina. Yonke le nkqubo idityaniswe ngaphandle komthungo ngenkqubo yolawulo ekrelekrele.

1. Umatshini wangaphambili wokubumba / we-hanger injection: ukubeka isiseko sobugcisa bokubumba obuchanekileyo

Njengokuqala komgca wemveliso, umatshini wokubumba wangaphambili uthatha itekhnoloji yenaliti yoxinzelelo oluphezulu ukunyibilika kunye nokwenza iplastiki amasuntswana ePP kumaqondo obushushu aphezulu angama-180-220 ℃, kwaye uwafake kwizimboli zebhotile ngokubumba okuchanekileyo. Isizukulwana esitsha sezixhobo sixhotyiswe ngenkqubo ye-servo motor drive, enokunciphisa umjikelo wokubumba ukuya kwi-6-8 imizuzwana kunye nokulawula impazamo yobunzima bebhotile engenanto ngaphakathi kwe-± 0.1g. Uyilo lwesitayela se-hanger sinokugqibezela ngokuhambelanayo ukubunjwa kwentsimbi yokuphakamisa umlomo webhotile, ukudibanisa ngokuthe ngqo kwinkqubo yokuvuthela okulandelayo, ukuphepha umngcipheko wokuphatha ukungcola okwesibini kwiinkqubo zemveli.

2. Umatshini wokuvuthela ibhotile ngokuzenzekelayo: ngokufanelekileyo, ukonga amandla kunye nokuqinisekiswa komgangatho

Umatshini wokuvuthela ibhotile wamkela itekhnoloji yokubumba inyathelo elinye (ISBM). Ngaphantsi kwesenzo se-biaxial directional stretching, ibhotile engenanto ishushu, yoluliwe, kwaye ivuthe ibunjwe ngaphakathi kwe-10-12 imizuzwana. Isixhobo sixhotyiswe ngenkqubo yokulawula ubushushu be-infrared ukuqinisekisa ukuba impazamo yobunzima bobunzima bomzimba webhotile ingaphantsi kwe-5%, kwaye uxinzelelo oluqhumayo lungaphezulu kwe-1.2MPa. Ngokusebenzisa iteknoloji yokulawula uxinzelelo oluvaliweyo, ukusetyenziswa kwamandla kuncitshiswe nge-30% xa kuthelekiswa nezixhobo zendabuko, ngelixa ufezekisa umphumo ozinzileyo weebhotile ze-2000-2500 ngeyure.

3. Ezintathu kumatshini omnye wokucoca, ukuzalisa kunye nokutywinwa: ingundoqo yokuvelisa i-aseptic

Esi sixhobo sidibanisa iimodyuli ezintathu eziphambili ezisebenzayo: ukucocwa kwe-ultrasonic, ukuzaliswa kobungakanani, kunye nokutywinwa okutshisa okunyibilikayo.

Iyunithi yokucoca: Ukwamkela inkqubo ye-multi-stage reverse osmosis yokujikeleza kwamanzi, idibene ne-0.22 μ m i-terminal filtration, ukuqinisekisa ukuba amanzi okucoca adibana nomgangatho we-pharmacopoeia we-WFI.

Iyunithi yokuzalisa: ixhotyiswe imitha yokuhamba esemgangathweni kunye nenkqubo yokubeka indawo ebonakalayo, kunye nokuchaneka kokuzaliswa kwe-± 1ml kunye nesantya sokuzalisa ukuya kwiibhotile ze-120 / ngomzuzu.

Iyunithi yokutywina: kusetyenziswa ubhaqo lwelaser kunye nobuchwepheshe bokutywinwa komoya oshushu, izinga lesiqinisekiso sokutywinwa lingaphezulu kwe-99.9%, kwaye amandla okutywina makhulu kune-15N/mm ².

Izinto eziluncedo zeteknoloji yomgca opheleleyo: impumelelo kubukrelekrele kunye nokuzinza

1. Inkqubo egcweleyo yenkqubo yoqinisekiso engenazintsholongwane

Umgca wemveliso uyilwe kunye nolawulo lwendawo ecocekileyo yokusingqongileyo (inqanaba le-ISO 8), i-laminar flow hood isolation, kunye nezixhobo zomphezulu we-electrolytic polishing, ezidityaniswe ne-CIP / SIP ye-intanethi yokucoca kunye nenkqubo yokucoca inzala, ukuhlangabezana neemfuno ze-GMP eziguquguqukayo ze-A-level zokucoceka kunye nokunciphisa umngcipheko wokungcoliswa kwe-microbial ngaphezu kwe-90%.

2. Ulawulo lwemveliso olukrelekrele

Ixhotyiswe ngenkqubo yokwenziwa kwemveliso ye-MES, ukujonga ixesha lokwenyani kwezixhobo ze-OEE (ubuchule obubanzi besixhobo), inkqubo yokutenxa isilumkiso separamitha, kunye nokuphucula isantya semveliso ngohlalutyo olukhulu lwedatha. Izinga lokuzenzekelayo lomgca wonke lifikelele kwi-95%, kwaye inani lamanqaku okungenelela ngesandla liye lancitshiswa libe ngaphantsi kwe-3.

3. Utshintsho lwemveliso eluhlaza

I-100% yokusetyenziswa kwakhona kwezinto zePP ihambelana neendlela zokusingqongileyo. Umgca wemveliso unciphisa ukusetyenziswa kwamandla nge-15% ngokusebenzisa izixhobo zokubuyisela ubushushu benkunkuma, kunye nenkqubo yokuhlaziya inkunkuma yonyusa izinga lokuphinda lisetyenziswe kwizinto ezilahliweyo ukuya kuma-80%. Xa kuthelekiswa neebhotile zeglasi, izinga lomonakalo wokuthuthwa kweebhotile zePP liye lancipha ukusuka kwi-2% ukuya kwi-0.1%, kwaye i-carbon footprint iye yancitshiswa ngama-40%.

Amathuba emarike: ukukhula okuphindwe kabini okuqhutywa yimfuno kunye nokuphindaphindwa kwetekhnoloji

1. Amathuba okwandisa imarike yehlabathi

NgokoPhando lweGrand View, imakethi yehlabathi jikelele yokufakwa kwi-intravenous kulindeleke ukuba yande ngesantya sokukhula esihlanganisiweyo sonyaka nge-6.2% ukusuka ngo-2023 ukuya ku-2030, kunye nobungakanani bemakethi yebhotile yokufakwa kwePP engaphezulu kwe-4.7 yeebhiliyoni zeedola ngo-2023.

2. Isikhokelo sophuculo lobugcisa

Imveliso eguquguqukayo: Phuhlisa inkqubo yokutshintsha ngokukhawuleza ukubumba ukufezekisa ixesha lokutshintsha elingaphantsi kwemizuzu engama-30 kwiintlobo zebhotile ezininzi ukusuka kwi-125ml ukuya kwi-1000ml.
Uphuculo lweDijithali: Ukwazisa itekhnoloji yamawele edijithali ye-debugging ebonakalayo, ukunciphisa umjikelo wokuhanjiswa kwezixhobo nge-20%.

Ukuveliswa kwezinto ezintsha: Ukuphuhlisa izixhobo ze-PP ze-copolymer ezixhathisayo kwi-gamma ray sterrilization kunye nokwandisa izicelo zabo kwintsimi yebhayoloji.

Ingokuzenzekelayo umgca wemveliso we-PP ibhotile IV isisombululoilungisa ngokutsha imbonakalo yomhlaba yeshishini lokupakisha lokufakwa kwi-intravenous ngokudityaniswa okunzulu koyilo lweemodyuli, ulawulo lobukrelekrele, kunye netekhnoloji yokuvelisa eluhlaza. Ngemfuno ye-homogenization yehlabathi jikelele yezibonelelo zonyango, lo mgca wemveliso odibanisa ukusebenza kakuhle, ukhuseleko, kunye nokukhuselwa kwendalo kuya kuqhubeka nokudala ixabiso kwishishini kwaye ube sisisombululo somgangatho wokuphucula izixhobo zonyango.