Embindini wempumelelo yale mihla ye-biopharmaceutical - ukusuka kwizitofu zokusindisa ubomi ukuya kwi-cut-edge monoclonal antibodies (mAbs) kunye neeproteni eziphinda ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde ziphinde zisebenze - kulele isixhobo esibalulekileyo: iBioreactor (Fermenter). Ngaphezu nje kwenqanawa, yindawo elawulwa ngobuchule apho iiseli eziphilayo zenza umsebenzi ontsonkothileyo wokuvelisa iimolekyuli zonyango. I-VEN imele phambili, ihambisa kungekuphela nje ii-bioreactors, kodwa izisombululo zobunjineli ezidibeneyo ezinika amandla eli shishini libalulekileyo.
Ukuchaneka kweNjineli yoBomi: Iimpawu eziphambili ze-VEN Bioreactors
VEN ii-bioreactorsziyilelwe ukuhlangabezana neemfuno ezichanekileyo zemveliso ye-biopharmaceutical:
Ukulawulwa kweNkqubo engahambelaniyo: Iinkqubo eziphezulu zilawula iiparitha ezibalulekileyo - ukushisa, i-pH, i-oksijeni echithwe (DO), ukuphazamiseka, ukondla izondlo - ngokuchanekileyo kunye nokuzinza okukhethekileyo, ukuqinisekisa ukukhula kweeseli ezifanelekileyo kunye nomgangatho wemveliso ohambelanayo.
I-Scalability & Flexibility: Isikali esingenamthungo ukusuka kwiiyunithi ze-benchtop yebhubhoratri ye-R & D kunye nophuhliso lwenkqubo, ngokusebenzisa i-bioreactors ye-pilot-scale, ukuya kwiinkqubo ezinkulu zemveliso, ngelixa ligcina inkqubo yokungaguquguquki.
I-Sterlity Assurance: Eyenziwe ngokucwangciswa kococeko (izakhono ze-CIP / SIP), izinto eziphezulu eziphezulu (i-316L insimbi engenasici okanye i-polymers biocompatible), kunye nezitywina ezinamandla zokuthintela ukungcoliseka - eyona nto ibalulekileyo kwi-GMP yokuvelisa.
Ukuxutywa okuPhakamileyo kunye nokuThuthukiswa koMninzi: Uyilo oluphuculweyo lwe-impeller kunye ne-sparger luqinisekisa ukuxubana okulinganayo kunye nokuhanjiswa kwe-oksijini okusebenzayo, okubalulekileyo kwiinkcubeko zeeseli ze-mammalian ezixineneyo.
Ukubeka iliso okuPhambili kunye nokuSebenza: Iinzwa ezidibeneyo kunye neenkqubo zokulawula eziyinkimbinkimbi (i-SCADA / i-MES ehambelanayo) ibonelela ngedatha yexesha langempela kwaye yenza ulawulo lwenkqubo oluzenzekelayo ukwenzela ukuthembeka okuphuculweyo kunye nokuthembeka kwedatha.
I-Driving Innovation kwiMveliso yaMayeza
IVEN i-bioreactors zizixhobo eziyimfuneko kuwo wonke umzobo we-biopharma:
Ukuveliswa kweSitofu sokugonya: Ukuhlakulela iiseli ezincancisayo (umzekelo, iVero, i-MDCK) okanye ezinye iiseli zeeseli ukuvelisa i-viral vectors okanye i-antigens kwizitofu zokugonya zesizukulwana esilandelayo.
Ii-Antibodies ze-Monoclonal (mAbs): Ukuxhasa ukuveliswa kwemveliso ephezulu yee-antibodies eziyinkimbinkimbi zonyango usebenzisa i-CHO, i-NS0, okanye i-SP2 / 0 imigca yeseli eqinile.
I-Recombinant Protein Therapeutics: Ukwenza ukubonakaliswa okusebenzayo kunye nokukhuselwa kweeprotheyini ezibalulekileyo ezifana neehomoni, ii-enzymes, kunye nezinto ezikhulayo.
I-Cell & Gene Therapy (CGT): Ukuququzelela ukwanda kweevektha zentsholongwane (umzekelo, i-AAV, i-Lentivirus) okanye iiseli zonyango ngokwazo ngokunqunyanyiswa okanye kwiifomathi zokubambelela.
Ubuchwephesha beNkcubeko yeeSeli zeMammalian: I-VEN igxile kwiimfuno ezintsonkothileyo zeenkqubo zeseli ye-mammalian, ebonelela ngezisombululo ezilungiselelwe imigca yeeseli ezibuthathaka.
Ngaphaya kwe-Bioreactor: I-VEN Advantage - Iqabane lakho leSiphelo ukuya esiphelweni
U-IVEN uyayiqonda into yokuba i-bioreactor yinxalenye ye-ecosystem yokuvelisa. Sinikezela ngezisombululo zobunjineli ezibanzi, ezintsha ezigubungela umjikelo wobomi beprojekthi:
Ubunjineli beNgcali kunye noYilo: Iqela lethu lenza uhlengahlengiso oluphuculweyo, olusebenzayo, kunye noyilo oluhambelanayo lwendawo kunye noyilo lwenkqubo olulungiselelwe ialekyuli yakho ethile kunye nesikali.
I-Precision Fabrication: Imveliso ye-state-of-art iqinisekisa umgangatho ophezulu wemigangatho ye-bioreactor skids, iinqanawa, iimodyuli zombhobho (pre-fab / PAT), kunye neenkqubo ezincedisayo.
IProjekthi eLungelweyo kunye noLawulo loLwakhiwo: Silawula ukuntsonkotha, siqinisekisa ukuba iprojekthi yakho - ukusuka kwiplanti yokulinga ukuya kwiziko elipheleleyo le-GMP - inikezelwa ngexesha kunye nohlahlo lwabiwo-mali.
Inkxaso yokuqinisekisa: Uncedo olupheleleyo kunye ne-DQ, i-IQ, i-OQ, iiprotocol ze-PQ kunye nokwenziwa, ukuqinisekisa ukulungela ukulawula (i-FDA, i-EMA, njl.).
INkonzo yeHlabathi kunye neNkxaso: Iinkqubo zokulungiswa okusebenzayo, ukucombulula ingxaki yokuphendula ngokukhawuleza, iindawo ezisecaleni, kunye nobuchule bokwenza inkqubo yokwandisa ixesha lokusebenzela kunye nemveliso.
Nokuba unguvulindlela othe ngxi kwilebhu, unyusa umgqatswa othembisayo, okanye uqhuba imveliso yorhwebo ephezulu, i-IVEN liqabane lakho elizinikeleyo. Sinikezela ngeenkqubo zobuqu ze-bioreactor kunye nezisombululo zobunjineli ezipheleleyo - ukusuka kwingcamango yokuqala ngoyilo, ukwakha, ukuqinisekiswa, kunye nenkxaso eqhubekayo yokusebenza.
Vula amandla apheleleyo enkqubo yakho yebhayoloji.Qhagamshelana ne-VENnamhlanje ukufumanisa ukuba itekhnoloji yethu ye-bioreactor kunye nobuchule bobunjineli obudibeneyo bunokuwukhawulezisa njani umendo wakho wokuhambisa amayeza atshintsha ubomi.
Ixesha lokuposa: Jun-30-2025