Kwimimandla ye-biotechnological kunye ne-biophamarutical, amagama athi "I-bioreactor" kunye "ne-biopesser" zihlala zisetyenziswa ngokuthe ngcembe, kodwa zibhekisa kwiinkqubo ezahlukeneyo ezinemisebenzi ethile kunye nezicelo. Ukuqonda umahluko phakathi kwezi ntlobo zimbini zezixhobo kubalulekile kubachwechwela ebaleni, ngakumbi xa beyilo kunye neenkqubo zokwenza izinto ezihlangabezana nomhlaba.

Amagama achazayo

I-Bioreactor ligama elibanzi eligubungela nasiphi na isikhongozelo apho kuye kwenzeka khona into eyenzekayo. Oku kunokubandakanya iinkqubo ezinjengokwahluka njengokubiwa, inkcubeko yeseli, kunye nokuphendula kwe-enzyme. I-Bioreactors zinokuyilwa kwiimeko ze-aerobic okanye kwiimeko ze-anaerobic kwaye zikwazi ukuxhasa uluhlu olubanzi lwezinto eziphilayo, kubandakanya iibhakteria, iigwele kunye neeseli zeMammalian. Baxhotyiswe ngeqondo lobushushu ezahlukeneyo, i-PH, inqanaba le-OXYGEN, kunye nokulawula ukulawula ukuqalisa ukukhula kwee-microorganism okanye iiseli.

I-bioperdmenimplate, kwelinye icala, luhlobo oluthile lwebhayilohati esetyenziswa ikakhulu kwiinkqubo zokubila. Ukubeleka yinkqubo ye-metabolic esebenzisa i-microgamenis, eyona ixhaphakileyo okanye intsholongwane, ukuguqula i-suads kwii-asidi, iigesi, okanye notywala.Iibhayimu zenzelwe ukudala imeko elungele ukukhula kwezi microorganis, ngaloo ndlela ivelisa iintlobo ezahlukeneyo zebhadiops ezifana ne-ethanol, i-acids, kunye namayeza.

Umahluko ophambili

Umsebenzi:

I-Bioreactors inokusetyenziselwa iintlobo ezahlukeneyo zebhadio, kubandakanya ukuphendula kwe-inkco kunye ne-enzyme, ngelixa i-Fermenvers iyilelwe ngokukodwa kwiinkqubo zokubiyela.

Inkcazo yoyilo:
Iibhayimuzihlala zilwe ngeempawu ezithile zokuhlangabezana neemfuno zezinto ezizondelayo. Umzekelo, banokubandakanya izinto ezinje ngee-baffles zokuphucula ukuxuba, iinkqubo zokuhambisa ii-aeratication zokubila kwe-aerobic, kunye neenkqubo zokulawula ubushushu ukugcina iimeko zokukhula okugqibeleleyo.

Isicelo:
I-Bioreactors ziguquguqukayo kwaye zinokusetyenziselwa izicelo ezahlukeneyo kumashishini ahlukeneyo, kubandakanya amayeza ahlukeneyo, ukutya kunye neziselo, kunye ne-biechch in biotechnology yendalo. Ngokwahlukileyo koko, i-Fermenters isetyenziswa ngokuyintloko kwimizi-mveliso evelisa iimveliso zokuvela, ezinje ngokubeka i-wayining, ukubopha, kunye nemveliso ye-biofuweli.

Isikali:
Zombini ezi bioreactors kunye ne-Fermeniters zinokwenziwa isikali esahlukileyo, ukusuka kuphando lwelebhu kwimveliso yamashishini. Nangona kunjalo, iifestile zihlala zinesikhundla esikhulu sokulungiselela inani elikhulu lemveliso eveliswa ngexesha lenkqubo yokuxhwalela.

Indima ye-GMP kunye ne-ASM-BPE kwi-Fermenter yoyilo

Ukuthobela imigangatho yolawulo kubalulekile xa kuziwa kuyilo kunye nokwenziwa kweI-Bio-Fersers. Kwi-Ivensi, siqinisekisa ukuba iziphene zethu zenziwe zaze zenziwa ngokuhambelana ngokungqongqo kwenkqubo yemveliso (i-GMP) kunye ne-Asme-BPE (izixhobo zaseMelika zeenjineli ze-biopeces. Oku kuzinikela kumgangatho kunye nokhuseleko kubalulekile kubathengi bethu be-biophamarcial abaxhomekeka kwizixhobo zethu zokufumana ububi be-robfial yenkcubeko.

BethuIitanki zokubiyelaInqaku lengcali, olusebenziseka lula kunye nemodyuli enokudityaniswa ngokulula kwiinkqubo ezikhoyo. Sinikezela ngeenqanawa ezihambelana nemigangatho yenqanawa yelizwe yoxinzelelo yelizwe, kubandakanya i-ASME-U, GB150 kunye ne-PED (i-PED (yoonoQOQO). Okubiwa kokutshintsha kuyakuqinisekisa ukuba iitanki zethu zinokufumana uluhlu olubanzi lweenkqubo kunye neemfuno zolawulo.

Ukwenza ngokwezifiso kunye nokungahambi kakuhle

E-Iven, siyaqonda ukuba umthengi ngamnye we-biopharmacerutical uneemfuno ezizodwa. Kungenxa yoko le nto sinikezela ngoluhlu olupheleleyo lwezinto ezifundwayo ukuze zilinywe intsholongwane, ukusuka elabhoratri R ukuya kwi-Pilot kunye nemveliso yemveliso. Abaphengululi bethu banokwenziwa ngokwezifiso kwiimfuno ezithile, kubandakanya umthamo, ukusukela kwiilitha ezi-5 ukuya kwi-30 yeekhilolimitha. Olu bhetyebhetye lusivumela ukuba sihlangabezane neemfuno zeentsholongwane ze-aerobic, ezinjenge-Escherichia Coli kunye nePichia Pagis, eziqhele ukusetyenziswa kwimveliso ye-byphaphaphaphaccec.

Ngesishwankathelo, ngelixa zombini ezi bioreactors kunyeIibhayimuDlala indima ebalulekileyo kwicandelo le-biotechnology, isetyenziselwa iinjongo ezahlukeneyo kwaye zenziwe ngemisebenzi eyahlukeneyo engqondweni. Ukuqonda lo mahluko kubalulekile ekukhetheni izixhobo ezifanelekileyo zesicelo esithile. E-Iven, sizimisele ukubonelela ngee-feermens ezikumgangatho ophezulu ezidibana neemfuno ezinqabileyo zoshishino lwe-biopharmacerutical, uqinisekisa ukuba abathengi bethu banokufumana iziphumo ezilungileyo kwiinkqubo zabo zokuhlaliswa kwe-micronial. Nokuba ukwinqanaba lokuqala lophando okanye ukutshayela imveliso yeshishini, ubungcali bethu kunye nezisombululo ezibonakalayo zinokukunceda ukuba uzithembe indlela ebubini yokuzithemba.